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Curbside Consultation in Neuro-Ophthalmology

Clinical Science

Impact of Laser Trabeculoplasty on Trabectome® Outcomes

Ophthalmic Surgery, Lasers and Imaging   Vol. 41   No. 4   July/August 2010
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Steven D. Vold, MD; Laurie Dustin, MS and the Trabectome Study Group

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BACKGROUND AND OBJECTIVE

To report the impact of prior laser trabeculoplasty on clinical outcomes of Trabectome (NeoMedix Corporation, Tustin, CA) surgery.

PATIENTS AND METHODS

This is a retrospective, non-comparative study of consecutive cases of Trabectome surgery with 36 months of follow-up. Main outcome measures were intraocular pressure (IOP), number of glaucoma medications, and the occurrence of secondary procedures.

RESULTS

In the trabeculoplasty group, mean IOP measured 16.5 ± 4.0 mm Hg with an average decrease of 24% from preoperative IOP at 12 months. In eyes without previous trabeculoplasty, IOP measured 15.7 ± 3.0 mm Hg with an average decrease of 30% at 12 months. Adjunctive medications decreased to 2.1 and 1.5 glaucoma medications, respectively. Secondary procedures were performed in 12% and 10% of eyes in each group.

CONCLUSION

Previous laser trabeculoplasty does not appear to significantly impact IOP, but may increase the need for glaucoma medication in patients undergoing Trabectome surgery.

[Ophthalmic Surg Lasers Imaging 2010;41:443-451.]

AUTHORS

From Boozman-Hof Regional Eye Clinic, P.A. (SDV), Rogers, Arkansas; and the Department of Preventive Medicine and Biostatistics (LD), University of Southern California, Los Angeles, California.

Originally submitted April 7, 2009. Accepted for publication February 19, 2010. Posted online May 28, 2010.

Presented at the American Glaucoma Society Annual Meeting, March 5-8, 2009, San Diego, California; the American Society of Cataract & Refractive Surgery Annual Meeting, April 3-8, 2009, San Francisco, California; and the World Glaucoma Congress, July 8-11, 2009, Boston, Massachusetts.

Supported by grants NIH-EY03040 and NIH-1R43-EY015037-01.

Dr. Vold is a Trabectome trainer for NeoMedix Corporation. Dr. Dustin has no financial or proprietary interest in the materials presented herein.

Address correspondence to Steven D. Vold, MD, Boozman-Hof Regional Eye Clinic, P.A., 3737 West Walnut, Rogers, AR 72756.

doi: 10.3928/15428877-20100525-06

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