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Curbside Consultation in Retina

Clinical Science

Intraocular Pressure and Visual Field Damage as Risk Factors for Visual Field Progression in Filtering Surgery

Ophthalmic Surgery, Lasers and Imaging   Vol. 41   No. 4   July/August 2010
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John S. Cohen, MD; Gary D. Novack, PhD and Jeffrey M. Zink, MD

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BACKGROUND AND OBJECTIVE

To evaluate the relationship between preoperative visual field severity and postoperative intraocular pressure as risk factors for visual field progression.

PATIENTS AND METHODS

Patients undergoing trabeculectomy (TRAB, n = 92 eyes of 73 patients) or combined trabeculectomy and cataract extraction by phacoemulsification (COMBO, n = 49 eyes of 41 patients) by one surgeon with at least 6 months of follow-up were reviewed.

RESULTS

Both the COMBO and TRAB treatment groups experienced a substantial decrease in mean intraocular pressure (4.7 ± 6.0 and 10.1 ± 6.5 mm Hg) and mean number of ocular hypotensive medications (1.8 ± 1.2 and 2.2 ± 1.5), respectively. In the subset of 47 eyes with reliable visual fields, the COMBO group experienced a mean improvement in mean deviation of 2.75 dB, and the TRAB group experienced only minimal changes in visual fields.

CONCLUSION

In general, visual fields did not worsen following trabeculectomy or combined surgery.

[Ophthalmic Surg Lasers Imaging 2010;41:452-458.]

AUTHORS

From the Cincinnati Eye Institute (JSC, JMZ); the University of Cincinnati School of Medicine (JSC, JMZ), Cincinnati, Ohio; and PharmaLogic Development, Inc. (GDN), San Rafael, California.

Originally submitted April 20, 2009. Accepted for publication February 25, 2010. Posted online May 28, 2010.

Presented in part as a poster at the American Glaucoma Society annual meeting, March 2-5, 2006, Charleston, South Carolina.

Funded in part by Research to Prevent Blindness, New York, New York, and the Elmer P. Robinson Research Fund, Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, Ohio.

The authors have no financial or proprietary interest in the materials presented herein.

This study is registered with www.clinicaltrials.gov as NCT00327405.

Address correspondence to John S. Cohen, MD, Cincinnati Eye Institute, 1945 CEI Drive, Cincinnati, OH 45242.

doi: 10.3928/15428877-20100525-03

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